Researchers from McMaster University in Hamilton, Ont., used mice genetically engineered to age quickly to compare the effects of a lifetime of activity versus a sedentary life. The study is published in the journal Proceedings of the National Academy of Science.
What made the difference was endurance exercise. The active mice jogged briskly on treadmills three days a week for 45 minutes. After five months, premature aging was halted in practically every organ of the mice that exercised. The mice that slacked off were graying, balding, less fertile and socially isolated.
Their muscle tissue exhibited signs indicating damage, while the muscles of the mice that exercised were perfectly normal.
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